140929093856-large-790x481The basis for cognitive decline remains largely unknown but scientists from the Weizmann Institute have uncovered evidence of a biochemical signature that is the culprit of an aging brain.  Remarkably, shutting down the signaling pathway that is the basis for the signature using an inhibitory antibody not only induced growth of new neurons in the hippocampus, the long term memory center of the brain, but also improved performance on cognitive tasks in a group of aged mice.  The same signature is found in human brain tissue in the analogous part of the brain, suggesting that some of the age-related cognitive decline in humans could be caused by the same mechanisms and reversible with treatment. At Neomatica